AMANAKA FACTORS OPTIMIZATION FORMULA — Phytochemical Support for Safer Cellular Reprogramming
Support Safer Cellular Reprogramming with Yamanaka Factors Optimization Formula
Designed as an adjunctive phytotherapeutic matrix, this formula provides protective and regulatory signals to enhance OSKM (Yamanaka factors) reprogramming efficiency while helping suppress tumorigenic and stress pathways—aiming to promote controlled, partial rejuvenation without tipping cells toward uncontrolled proliferation.
What are the Yamanaka factors?
The Yamanaka factors (OSKM) are four transcription factors — Oct4, Sox2, Klf4, and c‑Myc — used to reset somatic cells toward a pluripotent, youthful state. While powerful for inducing cellular reprogramming and rejuvenation, they carry risks (notably c‑Myc’s oncogenicity and potential genomic instability) that motivate strategies to optimize safety.
WHAT’S INSIDE?
A synergistic blend of longevity‑focused botanicals and protective phytochemicals from multiple traditions, selected to support genomic stability, proteostasis, antioxidant defenses, and controlled epigenetic remodeling:
- Adaptogenic and stress‑buffering herbs (e.g., Withania/Ashwagandha, Rhodiola) — support cellular stress resilience and balanced stress signaling.
- Polyphenol‑rich modulators (e.g., Curcuma/Curcumin, resveratrol sources) — antioxidant, anti‑inflammatory, and epigenetic‑modulating actions that protect DNA and reduce aberrant signaling.
- Proteostasis and autophagy supporters (e.g., Green Tea/EGCG, Andrographis, soursop components) — enhance protein quality control and clearance of damaged proteins.
- Senescence‑modulating botanicals (e.g., quercetin/fisetin sources, licorice compounds) — senolytic/senomorphic activity to reduce SASP and senescent burden.
- Mitochondrial and metabolic stabilizers (e.g., Panax ginseng, berberine‑containing plants) — support energy regulation, AMPK/SIRT pathways, and metabolic homeostasis.
- Epigenetic and DNA‑repair supportive extracts (e.g., Centella, Astragalus components) — promote repair pathways and healthier chromatin states.
WHY CHOOSE THIS FORMULA?
- Multi‑layered protection: combines antioxidants, proteostasis support, senescence modulators, and metabolic stabilizers to buffer reprogramming stressors.
- Designed to amplify beneficial reprogramming effects while reducing oncogenic and genomic‑instability risks.
- Integrates evidence‑informed botanicals from TCM, Ayurveda, and Western herbalism in a condensed, practitioner‑grade matrix.
WHO IS IT FOR?
Researchers, clinicians, and informed users exploring adjunctive botanical support during experimental or clinician‑supervised cellular reprogramming protocols, or individuals seeking systemic support for cellular resilience during longevity interventions. Not a replacement for clinical oversight.
HOW TO USE
Use per practitioner guidance or product labeling