Senescence Reduction and Cellular Rejuvenation Formula

The Senescence Reduction Formula combines natural senolytic and senomorphic botanicals to selectively eliminate senescent cells or suppress their harmful secretions (SASP). By reducing cellular senescence, the formula aims to improve tissue function, lower chronic inflammation, and create a cellular environment more receptive to regenerative therapies.

Ingredients and actions

• Quercetin (from plant flavonoids): senolytic activity in combination therapies; reduces SASP and oxidative stress.
• Fisetin (from persimmon, strawberries): natural senolytic shown to selectively induce apoptosis in senescent cells and reduce inflammatory secretions.
• Piperine (black pepper extract): enhances bioavailability of co-administered compounds and may support senomorphic effects.
• Curcuma longa (Turmeric/curcumin): anti-inflammatory and senomorphic properties that suppress SASP and support cellular resilience.
• Dasatinib (pharmaceutical-grade; microdosed when used in protocols) OR alternative botanical mitotic regulators (specify based on product version): enhances clearance of senescent cells when combined with flavonoid senolytics (included only in clinically directed formulations).
• Epigallocatechin gallate (EGCG, from Green Tea): antioxidant and senomorphic activity; reduces pro-inflammatory signaling.
• Resveratrol (Polygonum cuspidatum / Japanese knotweed): supports cellular stress responses, longevity pathways, and may complement senolytic action.

Key benefits

• Reduces senescent cell burden (senolytic support) and suppresses harmful SASP factors (senomorphic support).
• Lowers chronic, age-related inflammation and tissue dysfunction.
• Improves regenerative potential and responsiveness to reprogramming or reparative therapies.
• Supports overall cellular health, mitochondrial function, and longevity pathways.

Product attributes

• Combines evidence-backed natural senolytics and senomorphics in a targeted matrix
• Formulated for synergistic bioavailability (piperine, optimized extracts)
• Non-GMO, Gluten-free; organic extracts where possible
• Available in standard botanical-only and clinician-directed formulations (the latter may include microdosed pharmaceutical adjuncts per protocol)

Usage Intended as a periodic adjunctive protocol to reduce senescent cell load and support tissue rejuvenation. Follow recommended cycles and consult healthcare providers for clinician-directed versions.