Aging cells often suffer from mitochondrial dysfunction – reduced ATP output, more ROS, and metabolic inflexibility. Interestingly, during reprogramming to a pluripotent state, cells undergo a metabolic shift: old mitochondria are cleared via mitophagy and new, efficient mitochondria are biogenically produced, yielding a youthful metabolic profile. The Mitochondrial Biogenesis and Energy Formula similarly seeks to rejuvenate cellular powerhouses by triggering the production of fresh mitochondria and enhancing energy metabolis. In doing so, it supports the high energy demand of repair and reprogramming processes. The included phytochemicals activate master regulators like AMPK, PGC-1α, and SIRT1, which are known to drive mitochondrial biogenesis just as occurs in calorie restriction or exercise – interventions that extend lifespan by improving mitochondria.
