Cognilace™ contains Phytotherapeutic Extracts of Astragulus membracanus, Salvia miltiorrhiz, Radic Paoenia rubras, Polygonum multiflorum, Dryobalanops aromatica (Borneal), Callus spatholobi and Cinnamomum vera. The principal action of Cognilace is in modulating the Integrated Stress Response (ISR) by modulating the PERK pathways that induce the sustained PERK signaling associated with chronic or severe endoplasmic reticulum (ER) insults.